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In compacted materials, elastic anisotropy coupled with residual stresses could play a determining role in the manifestation of various types of defects such as capping and lamination, as it creates shear planes/bands and temporal relaxation. This internal micro-structure leads to time-delayed flaw initiation/formation, crack tip propagation under residual stresses, and ultimately product quality failures. Thus, their accurate characterization and variations are useful for understanding underlying failure mechanisms and to monitor variations in materials, processes and product quality during production prior to onset of failure. The extraction of tablet anisotropic elasticity properties is a challenging task, especially for commercial tablets with complex shapes, as shape often prevents the use of traditional destructive techniques (e.g., diametric compression testers) to produce accurate measurements. This study introduces and applies an ultrasonic approach to extracting the complete transverse isotropic elastic properties of compressed oral solid dosage forms to a commercial tablet product. A complete set of waveforms and the constitutive matrix for the compacted materials are reported. In addition, a perturbation analysis is carried out to analytically relate propagation speeds in various directions to the elastic coefficients. The proposed characterization approach is non-destructive, rapid, easy, and reliable in evaluating tablet anisotropy. |
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