Treatment of manic episodes in Scandinavia: the use of neuroleptic drugs in a clinical routine setting
| Autor: | L. Merinder, H. Lund, Rasmus Wentzer Licht, J. Dybbro, G. Gouliaev, Per Vestergaard |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Drug medicine.medical_specialty Pediatrics Bipolar Disorder Dose medicine.drug_class medicine.medical_treatment media_common.quotation_subject Scandinavian and Nordic Countries Severity of Illness Index behavioral disciplines and activities Antimanic Agents mental disorders medicine Humans Prospective Studies Age of Onset Psychiatry media_common Psychiatric Status Rating Scales Benzodiazepine Chemotherapy Mood stabilizer Middle Aged Psychiatry and Mental health Clinical Psychology Treatment Outcome Concomitant Female Scandinavia medicine.symptom Psychology Mania Antipsychotic Agents |
| Zdroj: | Licht, R W, Gouliaev, G, Vestergaard, P, Dybbro, J, Lund, H & Merinder, L 1994, ' Treatment of manic episodes in Scandinavia : the use of neuroleptic drugs in a clinical routine setting ', Journal of Affective Disorders, vol. 32, no. 3, pp. 179-85 . |
| ISSN: | 0165-0327 |
| DOI: | 10.1016/0165-0327(94)90016-7 |
| Popis: | To provide longitudinal data on the treatment of acute mania with neuroleptics in a routine setting, 125 consecutively admitted manic patients were examined. Out of the 125 patients, 111 (89%) were primarily treated with neuroleptics during the index episode, and a substantial use of drug combinations was observed. Of the 111 patients, 27% were still hospitalized and in a manic state after 10 weeks. Our results indicate that treatment under routine conditions is an outcome variable which is determined by the severity and persistence of the manic symptoms. If typical neuroleptics are used as first choice antimanic agents, dosages can be minimized by the concomitant use of a benzodiazepine. In non-responders, a mere shift from one neuroleptic to another does not seem rational, so to improve outcome, a mood stabilizer should be added. |
| Databáze: | OpenAIRE |
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