Copper–Calcium Hydroxide and Permanent Electrophoretic Current for Treatment of Apical Periodontitis

Autor: Aida Meto, Emiljano Tragaj, Bruna Colombari, Etleva Droboniku, Elisabetta Blasi, Agron Meto, Luca Fiorillo, Gabriele Cervino
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Histology
Electrophoretic current
Root canal
Radiography
Dentistry
root canal
Apical periodontitis
Copper–calcium hydroxide
Destructive focal sizes
Endodontic regeneration
Tooth discoloration
lcsh:Technology
Article
Lesion
copper–calcium hydroxide
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Apical periodontitis
Copper–calcium hydroxide
Destructive focal sizes
Electrophoretic current
Endodontic regeneration
Histology
Root canal
Tooth discoloration
Statistical significance
medicine
electrophoretic current
General Materials Science
030212 general & internal medicine
destructive focal sizes
lcsh:Microscopy
lcsh:QC120-168.85
Periodontitis
Calcium hydroxide
lcsh:QH201-278.5
business.industry
lcsh:T
030206 dentistry
apical periodontitis
medicine.disease
medicine.anatomical_structure
endodontic regeneration
chemistry
lcsh:TA1-2040
lcsh:Descriptive and experimental mechanics
lcsh:Electrical engineering. Electronics. Nuclear engineering
medicine.symptom
business
lcsh:Engineering (General). Civil engineering (General)
lcsh:TK1-9971
Zdroj: Materials, Vol 14, Iss 678, p 678 (2021)
Materials
Volume 14
Issue 3
ISSN: 1996-1944
Popis: Endodontic failure has been and continues to be a problem for endodontics-specialists. Complicated anatomy, numerous foramens, and accessory canals are an environment for microorganisms to infect the teeth. The purpose of the present work was to evaluate the regeneration of copper–calcium hydroxide (Cupral)-endodontically treated teeth diagnosed with apical periodontitis using an electrophoresis technique. In total, 132 patients, aging from 19 to 65 years old, underwent endodontic treatment mono- and multi-radicular teeth, with complicated canals from January 2019 to June 2020. The patients were divided into two groups: (i) the control group—which included 54 patients (n = 62 teeth) receiving endodontic paste (Calcipast + 1) and, as final filling, the AH-PlusTM cement—and (ii) the Cupral group, which included 78 patients (n = 80 teeth) receiving Cupral paste plus the electrophoretic current and, as final filling, the Atacamit-alkaline cement. The clinical cases were periodically observed along an 18-month follow-up period via radiography. Data were expressed as focal size of the lesions (mean ± standard error (SEM) of all the radiographic outcomes) observed in each group at each interval point. Statistical analysis was performed using the Student’s t-test that allowed us to compare the control and Cupral groups
the statistical significance was set at p <
0.05 and p <
0.01, where the latter was highly significant. Before treatments, the focal sizes were 4.8 mm and 4.95 mm for control and Cupral-treated groups, respectively. After 6 months, the mean focal sizes were 3.9 mm and 2.14 mm for the control and Cupral groups, respectively. After 12 months, in the control group, the mean focal size was measured at 2.8 mm, while, in Cupral group, the lesion size decreased down to 0.31 mm and a highly dynamic regeneration of the destructive focal-bone occurred. After 18 months, the lesions were further significantly reduced in the control group (mean values of 2.62 mm), while they were barely detectable in the Cupral group (0.2 mm). In conclusion, we provide initial evidence that the Cupral-electrophoresis methodology is effective in treating destructive periodontitis of teeth with problematic canals up to 18 months, thus allowing teeth preservation.
Databáze: OpenAIRE
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