Significant cardiac disease complicating Graves’ disease in previously healthy young adults
| Autor: | Ravikumar Ravindran, N Ubaysekara, S Rice, J K Witczak, Lakdasa Premawardhana, Z Yousef |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Weight loss Digoxin Hydrocortisone Carbimazole Endocrinology Diabetes and Metabolism Graves' disease Echocardiogram Cardiomyopathy Levothyroxine Pericardial effusion White Ibuprofen January Radionuclide therapy lcsh:Diseases of the endocrine glands. Clinical endocrinology Beta-blockers 0302 clinical medicine Ramipril Antibiotics Lisinopril Furosemide Palpitations FT3 Sinus rhythm FT4 Tremulousness Thyroid Goitre TSH Angiography Atrial fibrillation Propranolol Anti-thyroid autoantibodies Diarrhoea NSAID Thyrotoxicosis Thyroid antibodies 030220 oncology & carcinogenesis Cardiology Thyroidectomy Female Steroids medicine.symptom MRI Cardiac function curve Adult medicine.medical_specialty Peripheral oedema Prednisolone Thyroxine (T4) 030209 endocrinology & metabolism Cardiomegaly Heart failure Thyroid storm TSH receptor antibodies X-ray 03 medical and health sciences Internal medicine Fluid repletion Dyspnoea Internal Medicine medicine Hyperhidrosis Glucocorticoids Agitation lcsh:RC648-665 Radiotherapy business.industry Triiodothyronine (T3) medicine.disease Unique/Unexpected Symptoms or Presentations of a Disease United Kingdom Propylthiouracil Radioiodine business |
| Zdroj: | Endocrinology, Diabetes & Metabolism Case Reports Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2020) |
| ISSN: | 2052-0573 |
| Popis: | Summary Graves’ disease is associated with tachydysrythmia, cardiac ischaemia and cardiomyopathy – all uncommon in young adults without previous cardiac disease. We present three young individuals who developed cardiac complications after periods of uncontrolled Graves’ disease. Subject 1: A 34-year-old female had severe thyrotoxic symptoms for weeks. Investigations showed fT4: 98.4 (11–25 pmol/L), fT3: 46.9 (3.1–6.8 pmol/L), TSH 46.1; TSH Learning points: Cardiac complications of Graves’ disease are uncommon in young adults without previous cardiac disease. These complications may however occur if Graves’ disease had been poorly controlled for several weeks or months prior to presentation. Persistent symptoms after adequate control should alert clinicians to the possibility of cardiac disease. Specific treatment of Graves’ disease and appropriate cardiac intervention results in complete recovery in the majority and carries a good prognosis. Early definitive treatment should be offered to them to prevent cardiac decompensation at times of further relapse. |
| Databáze: | OpenAIRE |
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