REGULATION OF ANTIBODY FORMATION AGAINST HUMAN SERUM ALBUMIN IN RABBITS
| Autor: | B. Rubin, J. V. Spärck |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Immunodiffusion
medicine.medical_specialty Time Factors Immunization Secondary Stimulation Immunological memory Antigen Internal medicine medicine Animals Humans Antigens Serum Albumin biology Hemagglutination Tests General Medicine Human serum albumin Precipitin Tests Endocrinology Antibody Formation Immunology biology.protein Female Immunization Rabbits Antibody Antibody formation medicine.drug |
| Zdroj: | Acta Pathologica Microbiologica Scandinavica Section B Microbiology and Immunology. :305-313 |
| ISSN: | 0365-5563 |
| DOI: | 10.1111/j.1699-0463.1971.tb00066.x |
| Popis: | Both the time interval between two antigenic stimuli and the size of the primary and secondary antigen doses have been varied in a study on antibody formation against human serum albumin (HSA) in rabbits. It was found that the variation of the time interval between the primary and secondary stimulation did not significantly influence the amount of antibody produced in the secondary response. This was true whatever the size of the primary dose of antigen. However, when-rabbits were stimulated with the same primary antigen dose, the amount of antibody produced in the secondary response was closely correlated with the dose of antigen used for restimulation. The results are discussed in relation to present theories regarding the regulation on immunological memory. |
| Databáze: | OpenAIRE |
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