Transient lupus anticoagulant: an unusual cause of bruising in children
| Autor: | Liesner R, Mohan U, Anderson Ak |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Contusions Case Report Critical Care and Intensive Care Medicine New onset medicine Humans Child Lupus anticoagulant medicine.diagnostic_test business.industry Anticoagulant Excessive Bruising General Medicine Mixing study Antiphospholipid Syndrome medicine.disease Factor ii Dermatology Surgery Bleeding diathesis Lupus Coagulation Inhibitor Antibodies Antiphospholipid Emergency Medicine Female Partial Thromboplastin Time business Partial thromboplastin time |
| Zdroj: | Emergency Medicine Journal. 20:6e-6 |
| ISSN: | 1472-0213 1472-0205 |
| DOI: | 10.1136/emj.20.5.e6 |
| Popis: | A child presented with excessive bruising and prolonged activated partial thromboplastin time. Mixing studies in plasma were positive for phospholipid dependence of the anticoagulant, confirming a diagnosis of lupus anticoagulant. Factor II level was reduced. Laboratory findings normalised after three months, with spontaneous resolution of bruising. This case demonstrates a transient antiphospholipid antibody syndrome as a rare presentation of bleeding diathesis in a previously healthy child, and should be considered in children with new onset bruising and prolonged activated partial thromboplastin time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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