Biological roles and an evolutionary sketch of the GRF-GIF transcriptional complex in plants
| Autor: | Jeong Hoe Kim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Transcriptional Activation
Evolution Plant Development Organogenesis Computational biology Biology Genes Plant Biochemistry DNA-binding protein Chromatin remodeling 03 medical and health sciences Gene Expression Regulation Plant Transcription (biology) microRNA Gene family Receptors Growth Factor Molecular Biology Transcription factor GIF 0303 health sciences Organ growth miR396 030302 biochemistry & molecular biology General Medicine Plants Biological Evolution Invited Mini Review DNA-Binding Proteins MicroRNAs GRF Trans-Activators Intercellular Signaling Peptides and Proteins Transcription Factors |
| Zdroj: | BMB Reports |
| ISSN: | 1976-670X |
| DOI: | 10.5483/bmbrep.2019.52.4.051 |
| Popis: | GROWTH-REGULATING FACTORs (GRFs) are sequencepecific DNA-binding transcription factors that regulate various aspects of plant growth and development. GRF proteins interact with a transcription cofactor, GRF-INTERACTING FACTOR (GIF), to form a functional transcriptional complex. For its activities, the GRF-GIF duo requires the SWITCH2/ SUCROSE NONFERMENTING2 chromatin remodeling complex. One of the most conspicuous roles of the duo is conferring the meristematic potential on the proliferative and formative cells during organogenesis. GRF expression is post-transcriptionally down-regulated by microRNA396 (miR396), thus constructing the GRF-GIF-miR396 module and fine-tuning the duo's action. Since the last comprehensive review articles were published over three years ago, many studies have added further insight into its action and elucidated new biological roles. The current review highlights recent advances in our understanding of how the GRF-GIF-miR396 module regulates plant growth and development. In addition, I revise the previous view on the evolutionary origin of the GRF gene family. [BMB Reports 2019; 52(4): 227-238]. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|