Assessment of Non-contrast-enhanced Dixon Water-fat Separation Compressed Sensing Whole-heart Coronary MR Angiography at 3.0 T: A Single-center Experience
| Autor: | Hongfei Lu, Hang Jin, Mei-Ying Ge, Shihai Zhao, Yinyin Chen, Jianying Ma, Shan Yang, Mengsu Zeng, Jia‐jun Guo |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Coronary angiography
Contrast Media Coronary Angiography Single Center Imaging phantom Magnetic resonance angiography 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences 0302 clinical medicine medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies medicine.diagnostic_test business.industry Coronary Stenosis Mr angiography Water medicine.disease Coronary Vessels Magnetic Resonance Imaging Coronary arteries medicine.anatomical_structure Compressed sensing 030220 oncology & carcinogenesis business Nuclear medicine Magnetic Resonance Angiography |
| Zdroj: | Academic Radiology. 29:S82-S90 |
| ISSN: | 1076-6332 |
| DOI: | 10.1016/j.acra.2021.05.009 |
| Popis: | The clinical utility of Dixon water-fat separation coronary MR angiography (CMRA) with compressed sensing (CS) reconstruction has not been determined in a patient population. This study was designed to evaluate the performance of 3.0 T non-contrast-enhanced Dixon water-fat separation CS whole-heart CMRA sequence in vitro and in vivo.In vitro phantom MRI, we compared key parameters of the SENSE and CS images. And in this prospective in vivo study, from November 2019 to October 2020, 94 participants were recruited for 3.0 T non-contrast-enhanced Dixon water-fat separation CS whole-heart CMRA. The accuracy of CMRA for detecting a ≥ 50% reduction in diameter was determined using X-ray coronary angiography (CA) as the reference method.Compared with SENSE, CS with an appropriate acceleration factor offers both higher SNR/CNR (p0.05) and a shortened acquisition. Fifty-eight patients successfully completed the CMRA and CA. The sensitivity, specificity, positive predictive values, negative predictive values, and accuracy of 3.0 T non-contrast-enhanced Dixon water-fat separation CS whole-heart CMRA according to a patient-based analysis were 96.4%, 66.7%, 73.0%, 95.2% and 81.0%, respectively. The area under the receiver-operator characteristic (ROC) curve (AUC) of 3.0 T non-contrast-enhanced Dixon water-fat separation CS whole-heart CMRA for detecting significant coronary artery stenosis is 0.908, 0.895, and 0.904 in patient-, vessel-, and segment-based analyses respectively.3.0 T non-contrast-enhanced Dixon water-fat separation whole-heart CMRA using appropriate CS is a promising noninvasive and radiation-free technique to detect clinically significant coronary stenosis on patients with suspected CAD. |
| Databáze: | OpenAIRE |
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