Auditory P50 obtained with a repetitive stimulus paradigm shows suppression to high-intensity tones

Autor:	Takaharu Hayashida, Nobutada Tashiro, Toshiaki Onitsuka, Eigo Sato, Hideaki Ninomiya
Rok vydání:	2000
Předmět:	Adult Male medicine.medical_specialty Stimulation Audiology Stimulus (physiology) Stimulus modality medicine Humans Second-order stimulus Sound pressure Sensory gating General Neuroscience High intensity Electroencephalography General Medicine Psychiatry and Mental health Amplitude medicine.anatomical_structure Neurology Evoked Potentials Auditory Audiometry Pure-Tone Female Neurology (clinical) Psychology Neuroscience
Zdroj:	Psychiatry and Clinical Neurosciences. 54:493-497
ISSN:	1440-1819 1323-1316
DOI:	10.1046/j.1440-1819.2000.00741.x
Popis:	We manipulated stimulus intensity and number of frequency bands in auditory stimuli in order to investigate the nature of P50 in human auditory evoked potentials. Pure-tone and mixed-tone conditions were examined. For each condition, four stimulus intensities were used: 55, 70, 85 and 100 dB sound pressure level (SPL). The P50s were obtained at Cz using a repetitive stimulus paradigm. P50 amplitudes increased as stimulus intensities increased up to 85 dB; with 100 dB stimulation amplitudes decreased. The number of frequency bands in the stimulus did not affect P50 amplitude. Considered in terms of P50 suppression under a conditioning/testing paradigm, the results suggest that the P50 wave reflects activity of the sensory gating mechanism in humans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d36256ce7e73bc8e36bace793f1ea7 https://doi.org/10.1046/j.1440-1819.2000.00741.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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