Bordetella holmesii bacteremia: a newly recognized clinical entity among asplenic patients
| Autor: | Robyn M. Kaiser, David Lonsway, Colin W. Shepard, Marc Fischer, Jean B. Patel, Jean G. Jordan, Robbin S. Weyant, David A. Ashford, Roger E. Morey, Maryam I. Daneshvar |
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| Rok vydání: | 2003 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Heart disease Adolescent Bordetella Bacteremia Internal medicine Immunopathology RNA Ribosomal 16S Medicine Endocarditis Humans Blood culture Child Pathogen Aged Bordetella Infections Bordetella holmesii Aged 80 and over medicine.diagnostic_test biology business.industry Infant Middle Aged medicine.disease biology.organism_classification Antimicrobial Infectious Diseases Treatment Outcome Child Preschool Immunology Female business |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 38(6) |
| ISSN: | 1537-6591 |
| Popis: | Bordetella holmesii is a recently identified gram-negative bacterial species associated with bacteremia, endocarditis, and respiratory illness, mainly in immunocompromised patients. From isolates submitted to the Centers for Disease Control and Prevention from 1983 through 2000 for further identification, we identified 30 patients with B. holmesii bacteremia. Of the 26 patients for whom data were available, 22 (85%) were anatomically or functionally asplenic. In 25 (96%) of the 26 patients, B. holmesii was the only organism isolated from blood samples, and 14 patients (54%) had B. holmesii recovered fromor =2 blood cultures. The clinical course of the infection was generally characterized by a nonspecific febrile illness. Twenty-one patients (81%) were treated with various antimicrobial agents, and 20 (77%) were admitted to the hospital. There were no deaths. Our findings support evidence that B. holmesii may be a true pathogen associated with bacteremia among asplenic patients. |
| Databáze: | OpenAIRE |
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