Potent Bactericidal Antimycobacterials Targeting the Chaperone ClpC1 Based on the Depsipeptide Natural Products Ecumicin and Ohmyungsamycin A

Autor:	Paige M. E. Hawkins, David M. Hoi, Chen-Yi Cheung, Trixie Wang, Diana Quan, Vishnu Mini Sasi, Dennis Y. Liu, Roger G. Linington, Colin J. Jackson, Stefan H. Oehlers, Gregory M. Cook, Warwick J. Britton, Tim Clausen, Richard J. Payne
Rok vydání:	2022
Předmět:	Biological Products Bacterial Proteins Depsipeptides Drug Discovery Antitubercular Agents Molecular Medicine Animals Mycobacterium tuberculosis Peptides Cyclic Zebrafish Molecular Chaperones
Zdroj:	Journal of medicinal chemistry. 65(6)
ISSN:	1520-4804
Popis:	Ohmyungsamycin A and ecumicin are structurally related cyclic depsipeptide natural products that possess activity against
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c7407a67bac14efae151a19bc11014 https://pubmed.ncbi.nlm.nih.gov/35293761 Zobrazit plný text záznamu