Hepatitis B e antigen in volunteer and paid blood donors
| Autor: | M. Goldfield, Edward Tabor, H. C. Black, R. J. Gerety |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Volition
Hepatitis b e antigen Aging Hepatitis B virus HBsAg viruses Immunology Blood Donors medicine.disease_cause Hepatitis B Antigens Rheumatoid Factor Humans Immunology and Allergy Medicine Rheumatoid factor Hepatitis B Antibodies Volunteer Hepatitis B Surface Antigens biology business.industry virus diseases Hematology Hepatitis B Virology digestive system diseases Antibodies Anti-Idiotypic Titer HBeAg Immunoglobulin G biology.protein Antibody business |
| Zdroj: | Transfusion. 20:192-198 |
| ISSN: | 1537-2995 0041-1132 |
| DOI: | 10.1046/j.1537-2995.1980.20280169960.x |
| Popis: | Sera from 200 volunteer blood donors and 200 paid blood donors, all positive for hepatitis B surface antigen (HBsAg), were tested for the presence of hepatitis B e antigen (HBeAg). HBeAg was detected in 31 HBsAg-positive paid donors (15%), and in 11 HBsAg-positive volunteer donors (5%) by agar gel diffusion. The presence of HBeAg was associated with higher titers of HBsAg. No significant difference was found in the prevalence of antibody to HBeAg (anti-HBe) in the two donor groups. Rheumatoid factor was not associated with the presence or absence of HBeAg or anti-HBe, indicating that HBeAg is probably not an anti-IgG. These data support the epidemiological evidence that paid blood donors appear to be more likely than volunteer donors to transmit hepatitis B virus infection to recipients of their blood. |
| Databáze: | OpenAIRE |
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