Concise synthesis of marine natural products smenodiol and (−)-pelorol

Autor:	Yun-Fei Cheng, Hui-Jing Li, Xiao-Bo Wang, Yan-Chao Wu
Rok vydání:	2022
Předmět:	Organic Chemistry Plant Science Biochemistry Analytical Chemistry
Zdroj:	Natural Product Research. 37:1505-1510
ISSN:	1478-6427 1478-6419
DOI:	10.1080/14786419.2021.2023871
Popis:	A facile synthesis of marine natural product smenodiol has been achieved in 23.2% overall yield within 8 steps from readily available starting materials, which facilitates a concise synthesis of the marine natural product (−)-pelorol by employing a TMSOTf-mediated Friedel-Crafts reaction with a methyl ester in the aryl as the key step.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c2948e66da251fcafbbd41c8bc8d7f https://doi.org/10.1080/14786419.2021.2023871 Zobrazit plný text záznamu