Autor: |
Ngoc Quang Minh Ngo, Juliet E. Bryant, Jeremy Farrar, Hong Nhien Trinh, H. Rogier van Doorn, Bertrand De Meulder, Menno de Jong, Quang Tung Thai, Bao Tinh Le Binh, Quoc Bao Vo, Anh Tuan Tran, Lien Anh Ha Do, Thu Van Tran, Thanh Vu Vo, Johann Pellet, Thi Thu Loan Tran, Thi Dang, Jorrit-Jan H. Hofstra, Martin L. Hibberd, Quynh Huong Tran, Ngoc Huong Cao, Nguyen Anh Tran Dac, Charles Auffray, Thi Thanh Hai Nguyen, Huu Mai Khanh Nguyen, Bach Hue Nguyen, Lu Viet Ho, Minh Tien Nguyen |
Přispěvatelé: |
Medical Microbiology and Infection Prevention, AII - Amsterdam institute for Infection and Immunity, AII - Infectious diseases |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
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Zdroj: |
Journal of infectious diseases, 217(1), 134-146. Oxford University Press The Journal of Infectious Diseases |
ISSN: |
0022-1899 |
Popis: |
RSV infection induces a clearly different host response pattern compared with hRV and induced strong innate immune responses both locally and systemically. B cell lymphoma (BCL6) is a hub gene that positively correlates with RSV load and disease severity. Background Most insights into the cascade of immune events after acute respiratory syncytial virus (RSV) infection have been obtained from animal experiments or in vitro models. Methods In this study, we investigated host gene expression profiles in nasopharyngeal (NP) swabs and whole blood samples during natural RSV and rhinovirus (hRV) infection (acute versus early recovery phase) in 83 hospitalized patients |
Databáze: |
OpenAIRE |
Externí odkaz: |
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