Pregnancy in the Sickle Cell Disease and Fetomaternal Outcomes in Different Sickle cell Genotypes: A Systematic Review and Meta-Analysis

Autor:	null Teamur Aghamolaei, null Asiyeh Pormehr-Yabandeh, null Zahra Hosseini, null Nasibeh Roozbeh, null Mahdieh Arian, null Amin Ghanbarnezhad
Rok vydání:	2022
Předmět:	Genotype Anemia Sickle Cell Pregnancy Fetus Pregnancy Complications Meta-Analysis Cesarean Section Pregnancy Pregnancy Complications Hematologic Infant Newborn Pregnancy Outcome Humans Female General Medicine Anemia Sickle Cell
Zdroj:	Ethiopian Journal of Health Sciences; Vol. 32 No. 4 (2022)
ISSN:	2413-7170 1029-1857
Popis:	BACKGROUND: Pregnancy is a major concern among women with the sickle cell disease (SCD), and it is associated with increased adverse outcomes. The aim of the present meta-analysis is to report the fetomaternal outcomes in different sickle cell genotypes.METHODS: In this systematic review and meta-analysis, a comprehensive search of databases and search engines such as PubMed, Scopus, Web of Science, ProQuest, Cochrane Library, Science Direct and Google Scholar were performed. Any observational studies that had compared at least one outcome such as maternal outcomes, fetal outcomes, and morbidity between two groups of pregnant women with different types of sickle cell genotypes and pregnant women without SCD were evaluated.RESULTS: A total number of 9,827 pregnant women with SCD were examined. The results showed that pregnancy in SCD increased the risk of adverse outcomes for the mothers (including postpartum hemorrhage, prematurity, pregnancy-induced hypertension, pre-eclampsia, eclampsia, cesarean section, lower segment cesareansection, maternal death), fetus (including live births, low birth weight, intrauterine growth restriction, APGAR score at 5 min
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bccd7e5ee8e0b04405299f41c34978 https://pubmed.ncbi.nlm.nih.gov/35950054 Zobrazit plný text záznamu Plný text ve formátu PDF