Non-Cytopathic, Non-Productive Infection by Herpes Simplex Viruses Types 1 and 2
| Autor: | Brian R. McAuslan, Barry Garfinkle |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Serotype
Immunodiffusion viruses Fluorescent Antibody Technique HSL and HSV Biology Tritium Virus Replication Thymidine Kinase Genome Cell Line Mice chemistry.chemical_compound Antigen Virology Animals Humans Simplexvirus Carbon Radioisotopes Serotyping Antigens Viral Fibroblasts Rats Cell Transformation Neoplastic Infectious Diseases Avian Sarcoma Viruses Viral replication chemistry Thymidine kinase Cell culture Enzyme Induction DNA Viral DNA Thymidine |
| Zdroj: | Intervirology. 1:362-375 |
| ISSN: | 1423-0100 0300-5526 |
| DOI: | 10.1159/000148865 |
| Popis: | When RSV-transformed rodent cells were infected with either HSV type 1 or 2, the cells were not killed, but continued to grow and divide for at least ten passages. The HSV genome was partially expressed in these cells. Thymidine kinase was elicited and its synthesis was controlled. Indirect evidence suggests that limited herpes viral DNA synthesis occurred. Some HSV antigens were synthesized but the infection was non-productive. |
| Databáze: | OpenAIRE |
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