Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease
| Autor: | Laura Casaretti, Giovanni Esposito, Gianluigi Savarese, Roberta Esposito, Wanda Acampa, Caterina Marciano, Alberto Cuocolo, Dario Leosco, Giuseppe Rengo, Maurizio Galderisi, Carmen D'Amore, Pasquale Perrone-Filardi, Francesco Lo Iudice, Paola Gargiulo, Enza Capasso |
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| Přispěvatelé: | Marciano, C, Galderisi, M, Gargiulo, P, Acampa, W, D'Amore, C, Capasso, E, Savarese, G, Casaretti, L, Lo Iudice, F, Esposito, G, Rengo, G, Leosco, D, Cuocolo, A, Perrone-Filardi, P |
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Myocardial perfusion imaging business.industry Cardiovascular risk factors Type 2 Diabetes Mellitus General Medicine Type 2 diabetes medicine.disease Coronary artery disease Microvascular dysfunction Internal medicine Type 2 diabetes mellitus medicine Cardiology Radiology Nuclear Medicine and imaging In patient business Perfusion |
| Zdroj: | European journal of nuclear medicine and molecular imaging 39 (2012): 1199–1206. doi:10.1007/s00259-012-2117-9 info:cnr-pdr/source/autori:Marciano, Caterina; Galderisi, Maurizio; Gargiulo, Paola; Acampa, Wanda; D'Amore, Carmen; Esposito, Roberta; Capasso, Enza; Savarese, Gianluigi; Casaretti, Laura; Lo Iudice, Francesco; Esposito, Giovanni; Rengo, Giuseppe; Leosco, Dario; Cuocolo, Alberto; Perrone-Filardi, Pasquale/titolo:Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease/doi:10.1007%2Fs00259-012-2117-9/rivista:European journal of nuclear medicine and molecular imaging (Print)/anno:2012/pagina_da:1199/pagina_a:1206/intervallo_pagine:1199–1206/volume:39 |
| ISSN: | 1619-7089 1619-7070 |
| Popis: | We assessed the impact of type 2 diabetes, in the presence of other major cardiovascular risk factors, on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (CAD).In this prospective study, 23 patients with type 2 diabetes and 26 nondiabetic patients matched for age, sex and other cardiovascular risk factors underwent a cold pressure test (CPT) and dipyridamole transthoracic echocardiography to determine their coronary flow (CF) ratio. Within 2 weeks, all diabetic patients also underwent dipyridamole-rest myocardial perfusion single-photon emission (MPS) CT. None of the patients with or without diabetes had significant CAD on invasive coronary angiography. |
| Databáze: | OpenAIRE |
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