CT-guided percutaneous fine-needle aspiration biopsy of pulmonary nodules measuring 10 mm or less
| Autor: | Demetris Patsios, T. Chung, S J Herman, G. Weisbrod, A. Walsham, Narinder S. Paul, Y.L. Ng, H C Roberts |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Percutaneous Lung Neoplasms Biopsy Fine-Needle Thoracostomy Sensitivity and Specificity Carcinoma Non-Small-Cell Lung Biopsy medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Carcinoma Small Cell Lung Aged Aged 80 and over medicine.diagnostic_test business.industry Respiratory disease Pneumothorax Solitary Pulmonary Nodule Nodule (medicine) General Medicine Middle Aged medicine.disease Fine-needle aspiration Female Radiology medicine.symptom business Tomography X-Ray Computed |
| Zdroj: | Clinical radiology. 63(3) |
| ISSN: | 0009-9260 |
| Popis: | Aim To determine the value of computed tomography (CT)-guided fine-needle aspiration biopsy (FNAB) of small pulmonary nodules measuring 10 mm or less. Material and Methods CT-guided FNABs of 55 nodules, measuring 10 mm or less, were performed between January 2003 and February 2006. A coaxial technique was used, with an outer 19 G Bard Truguide needle and inner 22 G disposable Greene biopsy needle. Adequacy of specimens was assessed on-site by a cytotechnologist. The sizes of the nodules, distance from pleura, number of pleural punctures and aspirates, complications encountered, cytological diagnosis, and outcome were recorded. Results The mean nodule diameter was 9 mm (range 5–10 mm). The average distance from the costal pleura was 31 mm (range 0–88 mm). In 50 of the 55 FNABs, the pleura was crossed once. An average of four aspirates was performed per case. Twenty-five FNABs (45.5%) were adequate for diagnosis (24 malignant and one tuberculosis). In 11 cases, where no definite diagnosis was made following FNAB, the outcome was not affected. In 10 cases, samples were insufficient for diagnosis and the nodules were subsequently diagnosed as malignant. Eight cases were excluded in the final analysis as follow-up details were unavailable. The sensitivity for malignancy and overall accuracy were 67.7 and 78.8%, respectively. Pneumothorax occurred in 29 (52.7%) patients, with five (9.1%) requiring thoracostomy tubes. Conclusion CT-guided FNAB is a useful tool in the diagnosis and management of small pulmonary nodules, despite the lower diagnostic accuracy and higher complication rate than those of larger pulmonary lesions. |
| Databáze: | OpenAIRE |
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