An Analysis of Long-Term Outcomes in Patients Treated by Extensive Bowel Resection Due to Advanced Ovarian Cancer Relative to the Effectiveness of Surgery
| Autor: | Agnieszka Lewandowska, Katarzyna Lepinay, Antoni Sierant, Lukasz Wicherek, Sebastian Szubert |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Neoplasm Residual medicine.medical_treatment Rectum medicine Long term outcomes Humans In patient Adverse effect Aged Retrospective Studies Ovarian Neoplasms Advanced ovarian cancer Proctectomy business.industry Obstetrics and Gynecology Bowel resection Cytoreduction Surgical Procedures Middle Aged Debulking Bowel surgery Surgery Survival Rate medicine.anatomical_structure Treatment Outcome Reproductive Medicine Female business |
| Zdroj: | Gynecologic and obstetric investigation. 85(2) |
| ISSN: | 1423-002X |
| Popis: | Introduction: Surgery for advanced ovarian cancer (AOC) often requires bowel resections. However, the impact of bowel surgery on patient overall survival (OS) has not yet been precisely determined. Objective: The aim of the study was to analyze the OS rates in a group of AOC patients undergoing bowel resection. Methods: We carried out a retrospective analysis of patients who had undergone low anterior resection of the rectum (LAR) during primary or interval debulking surgery for AOC. We divided the patients into 2 groups: Group 1 included 69 patients who underwent only LAR; Group 2 included 66 patients who underwent LAR and additional bowel resection. The control group included 71 AOC patients who did not required bowel resection. Results: In the subgroup of patients with no gross residual disease (NGR), there were no differences in OS between Groups 1 and 2. In the subgroup of “optimally” (tumors Conclusions: Multiple bowel resections seem to improve OS in patients when NGR is achieved but should be avoided when complete resection is not possible. |
| Databáze: | OpenAIRE |
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