Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial (PAUSE-SCD): rationale and study design
| Autor: | Xianzhang Zhan, Younghoon Kim, Chenyang Jiang, Roderick Tung, Shih Ann Chen, Minglong Chen, Pause-Scd investigators, Hongde Hu, Shiro Nakahara, Kai Gu, Hailei Liu, Akiko Ueda, Jian Jiang, Yuki Komatsu, Kyoko Soejima, Yan Yao, Fa Po Chung, Ligang Ding, Akihiko Nogami, Ruhong Jiang, Shulin Wu, Yenn Jiang Lin, Yumei Xue, Yuichi Hori, Guosheng Fu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Asia Heart disease medicine.medical_treatment Population Cardiomyopathy Catheter ablation 030204 cardiovascular system & hematology law.invention Sudden cardiac death 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Physiology (medical) Internal medicine Clinical endpoint medicine Humans Prospective Studies 030212 general & internal medicine education Aged education.field_of_study business.industry Middle Aged medicine.disease Ablation United States Death Sudden Cardiac Research Design Catheter Ablation Tachycardia Ventricular Cardiology Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Interventional Cardiac Electrophysiology. 57:271-278 |
| ISSN: | 1572-8595 1383-875X |
| DOI: | 10.1007/s10840-019-00535-w |
| Popis: | The role of catheter ablation as an adjunct and alternative to ICD implantation is not known in patients at risk for recurrent ventricular tachycardia (VT) and sudden cardiac death (SCD) across Asia. Patients with nonischemic etiologies of cardiomyopathy, which are highly prevalent in Asia, have not been previously enrolled in randomized trials of VT ablation. To evaluate whether preemptive catheter ablation in patients with monomorphic VT and an indication for ICD implantation results in improved clinical outcomes compared to ICD implantation with standard medical therapy alone. To examine the natural history of ablation outcomes in the absence of background ICD therapy in patients that refuse randomization. The PAUSE-SCD study (NCT02848781) is a prospective, multi-center, randomized controlled trial enrolling patients with structural heart disease (EF |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink