Proceedings of the fourth international molecular pathological epidemiology (MPE) meeting
Autor: | Peter T. Campbell, Christine B. Ambrosone, Reiko Nishihara, Hugo J. W. L. Aerts, Melissa Bondy, Nilanjan Chatterjee, Montserrat Garcia-Closas, Marios Giannakis, Jeffrey A. Golden, Yujing J. Heng, N. Sertac Kip, Jill Koshiol, X. Shirley Liu, Camila M. Lopes-Ramos, Lorelei A. Mucci, Jonathan A. Nowak, Amanda I. Phipps, John Quackenbush, Robert E. Schoen, Lynette M. Sholl, Rulla M. Tamimi, Molin Wang, Matty P. Weijenberg, Catherine J. Wu, Kana Wu, Song Yao, Kun-Hsing Yu, Xuehong Zhang, Timothy R. Rebbeck, Shuji Ogino |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Patho-epidemiology
Cancer Research Meeting report Meeting summary BREAST-CANCER RISK Article COLORECTAL-CANCER PROSTATE-CANCER TUMOR MICROSATELLITE INSTABILITY COMPUTATIONAL PATHOLOGY ESTROGEN-RECEPTOR PHYSICAL-ACTIVITY Oncology Meeting proceedings LIQUID BIOPSY Molecular pathological epidemiology PROGESTERONE-RECEPTOR BODY-SIZE |
Zdroj: | Cancer Causes Control |
ISSN: | 0957-5243 |
DOI: | 10.1007/s10552-019-01177-z |
Popis: | An important premise of epidemiology is that individuals with the same disease share similar underlying etiologies and clinical outcomes. In the past few decades, our knowledge of disease pathogenesis has improved, and disease classification systems have evolved to the point where no complex disease processes are considered homogenous. As a result, pathology and epidemiology have been integrated into the single, unified field of molecular pathological epidemiology (MPE). Advancing integrative molecular and population-level health sciences and addressing the unique research challenges specific to the field of MPE necessitates assembling experts in diverse fields, including epidemiology, pathology, biostatistics, computational biology, bioinformatics, genomics, immunology, and nutritional and environmental sciences. Integrating these seemingly divergent fields can lead to a greater understanding of pathogenic processes. The International MPE Meeting Series fosters discussion that addresses the specific research questions and challenges in this emerging field. The purpose of the meeting series is to: discuss novel methods to integrate pathology and epidemiology; discuss studies that provide pathogenic insights into population impact; and, educate next-generation scientists. Herein, we share the proceedings of the Fourth International MPE Meeting, held in Boston, MA, USA on May 30(th) to June 1(st), 2018. Major themes of this meeting included ‘integrated genetic and molecular pathologic epidemiology’, ‘immunology-MPE’, and ‘novel disease phenotyping’. The key priority areas for future research identified by meeting attendees included integration of tumor immunology and cancer disparities into epidemiologic studies, further collaboration between computational and population-level scientists to gain new insight on exposure-disease associations, and future pooling projects of studies with comparable data. |
Databáze: | OpenAIRE |
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