The Comparative Associations of Ultrasound and Computed Tomography Estimates of Muscle Quality with Physical Performance and Metabolic Parameters in Older Men
| Autor: | Nilo A. Avila, Marc R. Blackman, Frank Liu, Syed H. Zaidi, Catheeja Ismail, Bryant A. Seamon, June Zhou, Courtney A Kassner, Michael O. Harris-Love, Bernadette Adams |
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| Rok vydání: | 2018 |
| Předmět: |
muscle tissue composition
Muscle tissue echogenicity lcsh:Medicine Adipose tissue 030209 endocrinology & metabolism Computed tomography muscle quality Article sarcopenia 03 medical and health sciences quantitative ultrasound 0302 clinical medicine myosteatosis medicine medicine.diagnostic_test business.industry lcsh:R aging Ultrasound Echogenicity computed tomography General Medicine medicine.disease metabolic status medicine.anatomical_structure Postprandial Sarcopenia muscle strength Lean body mass Nuclear medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Clinical Medicine Volume 7 Issue 10 Journal of Clinical Medicine, Vol 7, Iss 10, p 340 (2018) |
| ISSN: | 2077-0383 |
| Popis: | Estimates of muscle tissue composition may have greater prognostic value than lean body mass levels regarding health-related outcomes. Ultrasound provides a relatively low cost, safe, and accessible mode of imaging to assess muscle morphology. The purpose of this study was to determine the construct validity of muscle echogenicity as a surrogate measure of muscle quality in a sample of older, predominantly African American (AA) participants. We examined the association of rectus femoris echogenicity with mid-thigh computed tomography (CT) scan estimates of intra- and intermuscular adipose tissue (IMAT), basic metabolic parameters via blood sample analysis, muscle strength, and mobility status. This observational study was conducted at a federal medical center and included 30 community-dwelling men (age, 62.5 ± 9.2 AA, n = 24 Caucasian, n = 6). IMAT estimates were significantly associated with echogenicity (r = 0.73, p < 0.001). Echogenicity and IMAT exhibited similar associations with the two-hour postprandial glucose values and high-density lipoproteins values (p < 0.04), as well as grip and isokinetic (180° /s) knee extension strength adjusted for body size (p < 0.03). The significant relationship between ultrasound and CT muscle composition estimates, and their comparative association with key health-related outcomes, suggests that echogenicity should be further considered as a surrogate measure of muscle quality. |
| Databáze: | OpenAIRE |
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