USE OF OCTOGENARIAN LIVERS SAFELY EXPANDS THE DONOR POOL
| Autor: | D Rodrı́guez Romano, F Colina Ruíz, F. Palma Carazo, C Moreno Sanz, C. Jiménez Romero, I. Gonzalez Pinto, C. Loinaz Segurola, I García García, E. Moreno González, F Rodrı́guez González |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Orthotopic liver transplantation medicine.medical_treatment Liver transplantation Humans Medicine Donor pool health care economics and organizations Aged Aged 80 and over Transplantation business.industry Liver Diseases Graft Survival Age Factors food and beverages Middle Aged Tissue Donors humanities Liver Transplantation Surgery surgical procedures operative Waiting list Female Graft survival business Living donor liver transplantation |
| Zdroj: | Transplantation. 68:572-575 |
| ISSN: | 0041-1337 |
| Popis: | The increasing number of recipients on the waiting list for orthotopic liver transplantation (OLT) and the scarcity of donors contribute to recipient pretransplantation mortality. One important measure to increase the donor liver pool would be to accept the previously discarded donors who are more than 80 years old.From November 1996 to May 1998, four liver grafts from octogenarian donors (89, 87, 82, and 85 years old, respectively) were used for OLT. Pretransplantation donor and recipient characteristics and the evolution of recipients after OLT were analyzed.The donors did not present cardiac arrest or hypotension, and only low doses of vasopressors were required in three of them. Intensive care unit stay of the donors was from 12 to 24 hr. Cold ischemia time was from 4 hr to 8 hr 40 min. Mild microsteatosis was present in three donors and associated macrosteatosis of10% in one of these. Macroscopic appearance and consistency were normal in all four grafts. Posttransplantation evolution and follow-up were uneventful. Three recipients were alive and well at 24, 16, and 7 months; the second of these died at 16 months of recurrent viral C cirrhosis after a first OLT.The liver donor pool can be increased if liver grafts are accepted without an age limit but in good condition (hemodynamic stability, short intensive care unit stay, good liver function, soft consistency, cold ischemia time9 hr, and no severe steatosis). Octogenarian donors should be individually assessed in the absence of these ideal conditions. |
| Databáze: | OpenAIRE |
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