Evaluation of wound-healing potential of Catharanthus roseus leaf extract in rats
| Autor: | L. M. Pinto Pereira, Maria Inez Padula Anderson, BS Nayak |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Male
Catharanthus Wounds Penetrating Pharmacology law.invention Rats Sprague-Dawley Hydroxyproline chemistry.chemical_compound Dry weight law Drug Discovery medicine Animals Wound Healing integumentary system biology Apocynaceae Dose-Response Relationship Drug Plant Extracts Granulation tissue General Medicine Catharanthus roseus biology.organism_classification Rats Plant Leaves medicine.anatomical_structure Biochemistry chemistry Granulation Tissue Phytotherapy Wound healing |
| Zdroj: | Fitoterapia. 78(7-8) |
| ISSN: | 0367-326X |
| Popis: | Rats treated with 100 mg /kg/day of the Catharanthus roseus ethanol extract had high rate of wound contraction significantly decreased epithelization period, significant increase in dry weight and hydroxyproline content of the granulation tissue when compared with the controls. Wound contraction together with increased tensile strength and hydroxyproline content support the use of C. roseus in the management of wound healing. |
| Databáze: | OpenAIRE |
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