Severe acute respiratory syndrome in Singapore
| Autor: | I Chan, D Lim, P Choo, Janil Puthucheary, O M Chay |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Adolescent Physical examination macromolecular substances Neutropenia Severe Acute Respiratory Syndrome Epidemiology Disease Transmission Infectious Medicine Humans Respiratory system skin and connective tissue diseases Child Physical Examination Retrospective Studies Family Health Singapore medicine.diagnostic_test business.industry Respiratory disease fungi Infant Newborn Infant Retrospective cohort study Auscultation medicine.disease body regions Treatment Outcome El Niño nervous system Child Preschool Pediatrics Perinatology and Child Health Female Original Article business |
| Zdroj: | Archives of Disease in Childhood |
| ISSN: | 1468-2044 0003-9888 |
| DOI: | 10.1136/adc.2003.039420 |
| Popis: | Aims: To describe the epidemiological and clinical features of paediatric severe acute respiratory syndrome (SARS) in Singapore. Methods: The following data were retrospectively collected from the case records of all 71 patients (aged 7 months to 14 years) admitted from 23 March to 22 May 2003 to the SARS paediatric unit: patient demographics, contact history, clinical features, physiological parameters, investigations, treatment, and outcome. Using WHO criteria there were seven probable (P), 23 suspect (S), and 41 observe (O) cases. Results: Compared to the O cases P patients had a longer mean duration of fever (3.66 (SD 2.3) v 8.57 (SD 2.44) days), lower mean thrombocytopenia (248.3 (SD 82.7) v 173.7 (SD 49.0)×10 9 /l), leucopenia (8.19 (SD 4.45) v 3.06 (SD 1.02)×10 9 /l), lymphopenia (2.79 (SD 1.97) v 1.44 (SD 0.75)×10 9 /l), and neutropenia (4.48 (SD 2.88) v 1.24 (SD 0.43)×10 9 /l). Chest auscultation was abnormal in 71% of P patients, with mild crepitations detected. All had abnormal chest radiographs versus 39% of S cases, and 27% of O cases. Conclusions: There are no distinguishing clinical features of paediatric SARS. The diagnosis is suggested by the paucity of clinical signs with an abnormal chest radiograph, and laboratory evidence of leucopenia, lymphopenia, and thrombocytopenia. |
| Databáze: | OpenAIRE |
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