Long-term survival with thorotrast cervical granuloma

Autor: Stephen H. Miller, Richard J. Lung, Robert L. Harding, John C. Schantz, Stephen J. Herceg
Rok vydání: 1978
Předmět:
Zdroj: Journal of Surgical Oncology. 10:171-177
ISSN: 1096-9098
0022-4790
DOI: 10.1002/jso.2930100209
Popis: Thorium dioxide, a radioactive contrast material, was commonly used for cerebral angiography prior to recognition of its radiation hazard. Extravasation of the material into the extravascular tissue in the neck results in granuloma formation, thorotrastoma, long-term morbidity, and an increased incidence of benign and malignant tumors. We report our experience with the management of 2 patients who underwent cerebral angiography with thorotrast more than 25 years ago. Aggressive surgical excision of involved tissue is warranted to ameliorate symptoms and diminish the risk of malignancy.
Databáze: OpenAIRE