Relationship of fasting total homocysteine, high sensitivity C-reactive protein and features of the metabolic syndrome in Trinidadian subjects
| Autor: | Terence A. R. Seemungal, BS Nayak, A. Jagessar, Surujpaul Teelucksingh, Gershwin Davis, George Legall, L. M. Pinto Pereira |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Homocysteine Physiology Cross-sectional study Blood Pressure Logistic regression chemistry.chemical_compound Young Adult Risk Factors Physiology (medical) Internal medicine Diabetes mellitus medicine Diabetes Mellitus Humans Aged Metabolic Syndrome biology Triglyceride business.industry C-reactive protein General Medicine Fasting Middle Aged medicine.disease Blood pressure Endocrinology C-Reactive Protein Cross-Sectional Studies Trinidad and Tobago chemistry Cardiovascular Diseases Multivariate Analysis biology.protein Female Metabolic syndrome Waist Circumference business Biomarkers |
| Zdroj: | Archives of physiology and biochemistry. 119(1) |
| ISSN: | 1744-4160 |
| Popis: | To assess the relationship of homocysteine, hs-CRP, with known cardiovascular risk factors of the metabolic syndrome.Cross sectional study comprised 182 diabetic outpatients (70 males and 112 females), attending endocrinology clinics in Trinidad.Both male and females showed significant linear relationships between high sensitive C-reactive protein (hs-CRP), blood pressure and diabetes (r = -0.2R or R0.2). In females hs-CRP showed significant linear relationship with HDL, triglyceride, blood pressure and diabetes mellitus (p0.0001). The inverse relationship of hs-CRP with HDL implies the strong association of hs-CRP with metabolic syndrome. The multivariate logistic regression analysis showed significant relation of hs-CRP, metabolic syndrome and diabetes mellitus. There was no significant relationship of tHCY to any of the features studied.Serum C-reactive protein is significantly related to features of the metabolic syndrome. Total plasma homocysteine, appears to be independent of both hs-CRP and features of the metabolic syndrome. |
| Databáze: | OpenAIRE |
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