Supplementary Figure 5 from Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma

Autor: John M. Maris, Kristina A. Cole, Bruce Pawel, Andrew C. Wood, Robert W. Schnepp, Giordano Caponigro, Sudha Parasuraman, Sunkyu Kim, Sharon J. Diskin, Edward F. Attiyeh, Erica L. Carpenter, Yimei Li, Daniel Martinez, Lili T. Belcastro, Michael S. Nakazawa, Lori S. Hart, Mike R. Russell, JulieAnn Rader
Rok vydání: 2023
DOI: 10.1158/1078-0432.22451163
Popis: Supplementary Figure 5 - PDF file 138K, CDK4/6 inhibition does not induce cytotoxicity in neuroblastoma. (A) Caspase 3/7 activation and (B) PARP cleavage were not observed in cell lines with demonstrated sensitivity to LEE011. SN38, a known cytotoxic agent, was used as a positive control
Databáze: OpenAIRE