Platelet-rich plasma (PRP) for knee disorders
Autor: | Rik Kundra, Mohammad Shahid |
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Rok vydání: | 2017 |
Předmět: |
medicine.medical_specialty
platelet-rich plasma (PRP) medicine.medical_treatment Articular cartilage Osteoarthritis 03 medical and health sciences 0302 clinical medicine Medicine Knee articular cartilage Orthopedics and Sports Medicine In patient Platelet Autologous blood product Baseline values 030222 orthopedics business.industry meniscal injury 030229 sport sciences medicine.disease Surgery osteoarthritis Platelet-rich plasma Plasmapheresis business ligamentous injury |
Zdroj: | EFORT Open Reviews |
ISSN: | 2058-5241 2396-7544 |
Popis: | Platelet-rich plasma (PRP) is an autologous blood product with platelet concentrations above baseline values. The process involves the extraction of blood from the patient which is then centrifuged to obtain a concentrated suspension of platelets by plasmapheresis. It then undergoes a two-stage centrifugation process to separate the solid and liquid components of the anticoagulated blood. PRP owes its therapeutic use to the growth factors released by the platelets which are claimed to possess multiple regenerative properties. In the knee, PRP has been used in patients with articular cartilage pathology, ligamentous and meniscal injuries. There is a growing body of evidence to support its use in selected indications and this review looks at the most recent evidence. We also look at the current UK National Institute of Health & Clinical Excellence (NICE) guidelines with respect to osteoarthritis and the use of PRP in the knee.Cite this article: EFORT Open Rev 2017;2:28–34. DOI: 10.1302/2058-5241.2.160004. |
Databáze: | OpenAIRE |
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