Vitamin D status-associated postoperative complications in patients with hip dysplasia after periacetabular osteotomy: A case–control study
| Autor: | Kazuki Kitade, Taro Mawatari, Shoji Baba, Reima Sueda, Satoshi Hagio, Shinya Kawahara, Satoshi Ikemura, Yasuharu Nakashima |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Modern Rheumatology. |
| ISSN: | 1439-7609 1439-7595 |
| DOI: | 10.1093/mr/roac120 |
| Popis: | Objectives This study aimed to clarify the relationship between vitamin D status and complications after periacetabular osteotomy. Methods A total of 46 hips of 39 patients (3 men and 36 women; mean age at surgery, 41.0 years; mean postoperative follow-up duration, 63 months) were reviewed to obtain the following information: patients’ serum 25-hydroxyvitamin D [25(OH)D] status, prevalence of postoperative delayed union of osteotomy sites in the greater trochanter (DUGT) and ischiopubic stress fractures (IPSFs), and risk factors. Results The mean serum 25(OH)D level was 11.9 ng/ml. DUGT and IPSF were found in four (10.3%) and three (7.7%) patients, respectively. Serum 25(OH)D levels ≤ 11 ng/ml were significantly associated with DUGT in female patients (p = .02). Serum 25(OH)D levels ≤ 9 ng/ml and smoking were significantly associated with IPSF (p = 0.01 and 0.02, respectively). Overall, 21.7% of patients with serum 25(OH)D levels ≤ 11 ng/ml developed at least one complication; no complications occurred when serum 25(OH)D levels were >11 ng/ml. Conclusion Severe vitamin D deficiency was highly prevalent in relatively young patients. Vitamin D deficiency and smoking were independent risk factors for postoperative complications. Proactive supplementation is advisable to reduce postoperative complications, especially in patients with serum 25(OH)D levels ≤ 11 ng/ml. |
| Databáze: | OpenAIRE |
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