1,2-benzisothiazolin-3-one in disposable polyvinyl chloride gloves for medical use
| Autor: | Hely Reinikka-Railo, Kristiina Aalto-Korte, Jarmo Välimaa, Esa Leppänen, Riitta Jolanki, Maj-Len Henriks-Eckerman, Leena Ackermann |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Health Personnel Dentistry Dermatology Hand Dermatoses 1 2 benzisothiazolin 3 one Mass Spectrometry Health personnel chemistry.chemical_compound Immunology and Allergy Medicine Humans Polyvinyl Chloride Allergic contact dermatitis Finland business.industry Benzisothiazolinone technology industry and agriculture Patch Tests equipment and supplies medicine.disease Surgery body regions Dental personnel Thiazoles chemistry Dermatitis Occupational Contact allergy Dermatitis Allergic Contact Occupational exposure business Gloves Protective Contact dermatitis Chromatography Liquid Disinfectants |
| Zdroj: | Contact dermatitis. 57(6) |
| ISSN: | 0105-1873 |
| Popis: | Background: Benzisothiazolinone is used as a slimicide in the manufacture of disposable powder-free polyvinyl chloride (PVC) gloves. We recently reported 6 patients from dentistry and health care probably sensitized to benzisothiazolinone in PVC gloves. Objective: The study aimed to investigate how widely disposable PVC gloves for medical use on the Finnish market in 2006 contain benzisothiazolinone and to report new cases from 2 clinics in Helsinki. Methods: 31 brands of disposable PVC gloves were analysed for their benzisothiazolinone content. We looked through the patient material of Helsinki University Central Hospital to find benzisothiazolinone allergic patients. We also described 3 previously unpublished benzisothiazolinone allergic patients from Finnish Institute of Occupational Health. Results: 9 (30%) of the 31 glove brands contained 3–26 p.p.m. benzisothiazolinone. From the 2 clinics, we found 5 new benzisothiazolinone allergic patients who had used PVC gloves containing benzisothiazolinone. In addition, 3 patients had used disposable PVC gloves whose benzisothiazolinone content remained unknown. Conclusions: In Finland, benzisothiazolinone in powder-free PVC gloves has caused a small epidemic of allergic contact dermatitis in dental personnel and other health care workers. 1/3 of the disposable PVC gloves contained some benzisothiazolinone. A concentration of 20 p.p.m. benzisothiazolinone in a glove seems to be enough for sensitization. |
| Databáze: | OpenAIRE |
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