The dystroglycan: Nestled in an adhesome during embryonic development
| Autor: | Magdalena Hidalgo, Cathy Sirour, Valérie Bello, Thierry Darribère, N J Moreau, Nicolas Buisson |
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| Přispěvatelé: | Signalisation et morphogenèse = Signalling and morphogenesis (LBD-E12), Laboratoire de Biologie du Développement (LBD), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Association Francaise contre les Myopathies [13955], M. Curie University, CNRS, P. Curie University, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Embryonic Development
Biology Development Models Biological Extracellular matrix Dystroglycans 03 medical and health sciences 0302 clinical medicine Dystroglycan Extracellular Cell Adhesion Animals Humans Extracellular matrices Cell adhesion Molecular Biology [SDV.BDD]Life Sciences [q-bio]/Development Biology 030304 developmental biology 0303 health sciences Extracellular Matrix Proteins Cadherin Adhesome Gene Expression Regulation Developmental Cell Biology Cell biology biology.protein Signal transduction 030217 neurology & neurosurgery Developmental Biology Signal Transduction |
| Zdroj: | Developmental Biology Developmental Biology, Elsevier, 2015, 401 (1, SI), pp.132-142. ⟨10.1016/j.ydbio.2014.07.006⟩ Developmental Biology, 2015, 401 (1, SI), pp.132-142. ⟨10.1016/j.ydbio.2014.07.006⟩ |
| ISSN: | 0012-1606 1095-564X |
| DOI: | 10.1016/j.ydbio.2014.07.006⟩ |
| Popis: | International audience; Invertebrate and vertebrate development relies on complex processes that require many coordinated cell functions including cell adhesion, migration, proliferation and polarization. These processes depend on tissues and are spatio-temporally regulated by specific interactions between cells and between cells and the extracellular matrices. The dystroglycan, a transmembrane receptor that binds multiple extracellular matrix proteins, is expressed from oogenesis to organogenesis. There are increasing data suggesting that the axis, consisting of extracellular component-dystroglycan-cytoplasmic proteins, controls both the adhesion of cells to matrices as well as the transduction of signals coming from or directed to matrices. In this article, we review current advances leading to consider that the dystroglycan is a key protein nestled in an adhesome involved in mechanisms of cell adhesion during embryonic development. (C) 2014 Elsevier Inc. All rights reserved. |
| Databáze: | OpenAIRE |
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