Evaluation of Various Formulae for Glomerular Filtration Rate Estimation and Proposal of New Formulae for the Korean Population
| Autor: | Chang Kyu Lee, Young Kee Kim, Chae Seung Lim, Kyoung Ho Roh, Myung Hyun Nam, Kap No Lee, Chi Hyun Cho, Jang Su Kim |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Correlation coefficient Body Surface Area Clinical Biochemistry Renal function urologic and male genital diseases chemistry.chemical_compound Daily practice Republic of Korea Statistics Humans reproductive and urinary physiology Aged Retrospective Studies Mathematics Aged 80 and over Body surface area Creatinine Korean population Biochemistry (medical) Organotechnetium Compounds General Medicine Middle Aged Pentetic Acid Skeletal muscle mass female genital diseases and pregnancy complications chemistry Female Creatinine blood Algorithms Glomerular Filtration Rate |
| Zdroj: | Annals of Laboratory Medicine. 30:606-615 |
| ISSN: | 2234-3814 2234-3806 |
| DOI: | 10.3343/kjlm.2010.30.6.606 |
| Popis: | BACKGROUND: Some researchers have questioned the necessity of adjusting glomerular filtration rate (GFR) by body surface area (BSA). We compared the relationship between estimated GFR (eGFR) and radionuclide GFR (rGFR) with or without BSA adjustment by comparing the results obtained using various formulae with those obtained using 2 new proposed formulae. METHODS: A retrospective study was performed using 204 Korean individuals whose GFR had been estimated by the (99m)Tc-diethylenetriaminepentaacetic acid method between March 2004 and July 2008. We used the modification of diet in renal disease (MDRD) II formula, Mayo clinic quadratic (MCQ) formula, Cockcroft-Gault (CG) formula, and lean body mass-adjusted CG formula. Two new formulae, skeletal muscle mass index (SMI)-adjusted CG formula and SMI × 3.4/SCr, were proposed by us. We analyzed each parameter with Pearson's correlation coefficient and also obtained the bias values. RESULTS: BSA did not satisfy the fundamental prerequisites of an adjustment factor for rGFR. MDRD II and MCQ GFR estimates demonstrated higher Pearson's correlation coefficient with BSA-unadjusted rGFR than they did with BSA-adjusted rGFR. The other GFR formulae estimates showed better correlation with rGFR and more favorable bias (P |
| Databáze: | OpenAIRE |
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