Plasma concentrations of motilin and somatostatin are increased in late pregnancy and postpartum
| Autor: | Per G. Burhol, N. Holst, Trond Jenssen |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
medicine.medical_specialty Pregnancy Trimester Third Motilin Pregnancy Internal medicine Follicular phase Humans Medicine Prospective Studies Prospective cohort study reproductive and urinary physiology business.industry Postpartum Period Obstetrics and Gynecology medicine.disease Endocrinology Somatostatin Plasma concentration Gestation Female business hormones hormone substitutes and hormone antagonists Postpartum period |
| Zdroj: | BJOG: An International Journal of Obstetrics and Gynaecology. 99:338-341 |
| ISSN: | 1471-0528 1470-0328 |
| DOI: | 10.1111/j.1471-0528.1992.tb13735.x |
| Popis: | Objective To examine plasma levels of motilin and somatostatin throughout pregnancy. Design Prospective observational study. Setting University Hospital, Norway. Subjects Eight healthy pregnant women (aged 24–38 years) six of them primi-gravidae and eight healthy non-pregnant women of similar age with ovulatory menstrual cycles. Interventions In the pregnant women blood samples were obtained at 4-week intervals from 8 weeks gestation throughout pregnancy and again at 5 days and 28 days postpartum. In the non-pregnant controls blood samples were obtained on cycle days 4, 7, 10, 13, 14, 15, 18, 21 and 24. Main outcome measures Plasma levels of motilin and somatostatin. Results Plasma concentrations of both motilin and somatostatin rose continuously during pregnancy, and motilin levels increased still further to a peak of 165.1 (SE 35.8) pmol/1 at 5 days postpartum. Plasma motilin levels were significantly higher during the third trimester and at 5 days postpartum compared with non-pregnant controls (P |
| Databáze: | OpenAIRE |
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