Shorter incubation period is associated with severe disease progression in patients with COVID-19

Autor: Xuan Zhou, Zhiyu Li, Xuan Li, Fang Wang, Changxiang Lai, Zhiwei Li, Guohong Deng, Qiyuan Tang, Wenjie Xian, Mingbo Wang, Ruikun Chen, Xin Zhao, Rentao Yu
Rok vydání: 2020
Předmět:
Adult
Male
Microbiology (medical)
medicine.medical_specialty
Fever
Coronavirus disease 2019 (COVID-19)
Pneumonia
Viral
Immunology
Severe disease
Infectious and parasitic diseases
RC109-216
Biology
Microbiology
Gastroenterology
Infectious Disease Incubation Period
Incubation period
disease aggravation
Betacoronavirus
03 medical and health sciences
Internal medicine
medicine
Humans
Lymphocyte Count
Pandemics
incubation period
Proportional Hazards Models
Retrospective Studies
030304 developmental biology
0303 health sciences
SARS-CoV-2
030306 microbiology
Proportional hazards model
Incidence (epidemiology)
COVID-19
DISEASE AGGRAVATION
Retrospective cohort study
Middle Aged
CT scores
Prognosis
Hospitalization
Infectious Diseases
Disease Progression
Female
Parasitology
Coronavirus Infections
Tomography
X-Ray Computed
Research Article
Research Paper
Zdroj: Virulence
article-version (VoR) Version of Record
Virulence, Vol 11, Iss 1, Pp 1443-1452 (2020)
ISSN: 2150-5608
2150-5594
DOI: 10.1080/21505594.2020.1836894
Popis: The diagnosed COVID-19 cases revealed that the incubation periods (IP) varied a lot among patients. However, few studies had emphasized on the different clinical features and prognosis of patients with different IP. A total of 330 patients with laboratory-confirmed COVID-19 were enrolled and classified into immediate onset group(IP10 days, L group, 75 cases) based on IP. The difference of clinical characteristics and prognosis of the two groups were compared. There were more patients with fever in I group than in L group(P = 0.003), and counts of all the total lymphocytes, total T lymphocytes, CD4 + and CD8 + T lymphocytes were significantly different between the two groups(all P
Databáze: OpenAIRE
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