Hematoporphyrin derivative and laser photoradiation in the diagnosis and treatment of bladder cancer
| Autor: | Makoto Miwa, Harubumi Kato, Akira Tsuchiya, Yoshihiro Hayata, Nobuo Obara, Tetsutaro Ohi |
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| Rok vydání: | 1983 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Necrosis genetic structures Urology medicine.medical_treatment law.invention Lesion chemistry.chemical_compound law Edema Carcinoma Medicine Humans Aged Hematoporphyrin Carcinoma Transitional Cell Bladder cancer business.industry Middle Aged medicine.disease Laser Radiation therapy Hematoporphyrins chemistry Urinary Bladder Neoplasms Laser Therapy medicine.symptom business |
| Zdroj: | The Journal of urology. 130(1) |
| ISSN: | 0022-5347 |
| Popis: | Diagnosis and treatment of 8 patients with malignant bladder tumors were performed with intravenous administration of hematoporphyrin derivative, followed by krypton-ion laser violet light photo radiation and argon-dye laser red light photo radiation therapy. Fluorescence permitting localization and evaluation of the lesion was recognized in all 8 patients. Photo radiation with red argon-dye laser light obtained complete remission in 6 patients, with follow up from 6 to 18 months. To our knowledge this is the first report describing total regression of bladder tumors obtained byphotoradiation.Swelling and edema were noted within 20 minutes after argon-dye laser photo radiation therapy of bladder tumors. Necrosis and partial covering of the tumor by a whitish necrotic mass were noted after 3 days. The whitish mass covered the entire tumor at 7 to 14 days. Gradual exfoliation of the mass was followed by disappearance of the tumor and regeneration of normal mucosa at 9 to 10 weeks. |
| Databáze: | OpenAIRE |
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