Catalase, superoxide dismutase, glutathione reductase and thiobarbituric acid-reactive products in normal and dystrophic human muscle
| Autor: | Nirmal C. Kar, Carl M. Pearson |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Thiobarbituric acid
Clinical Biochemistry Glutathione reductase Biochemistry Muscular Dystrophies Lipid peroxidation chemistry.chemical_compound Human muscle In vivo Humans chemistry.chemical_classification biology Superoxide Dismutase Muscles Biochemistry (medical) General Medicine Catalase Thiobarbiturates Glutathione Reductase Enzyme chemistry biology.protein Indicators and Reagents CATALASE / Superoxide Dismutase |
| Zdroj: | Clinica Chimica Acta. 94:277-280 |
| ISSN: | 0009-8981 |
| DOI: | 10.1016/0009-8981(79)90076-7 |
| Popis: | The level of thiobarbituric acid-reactive products and the specific activities of catalase and glutathione reductase were significantly higher in muscles from patients with major forms of muscular dystrophies over those of control subjects. Superoxide dismutase activity was not altered in dystrophic muscles. These findings indicate the occurrence in human dystrophic muscles of an increased level of lipid peroxidation and the possible activation of certain enzymes that could conceivably inhibit lipid peroxidation in vivo. |
| Databáze: | OpenAIRE |
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