Permanent unilateral hearing loss after radiotherapy for parotid gland tumors
| Autor: | John T. M. Plukker, Remco de Bree, C. René Leemans, Cas Smits, Fred R. Burlage, Lisa van der Putten, Johannes A. Langendijk |
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| Přispěvatelé: | Faculteit Medische Wetenschappen/UMCG, Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Otolaryngology / Head & Neck Surgery, Radiation Oncology |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Hearing loss medicine.medical_treatment audiometry Hearing Loss Unilateral Radiation Dosage CT-planning parotid tumor NASOPHARYNGEAL CARCINOMA medicine otorhinolaryngologic diseases Humans Parotid Gland radiotherapy Aged Retrospective Studies hearing loss Aged 80 and over Postoperative Care medicine.diagnostic_test business.industry Radiotherapy Planning Computer-Assisted Retrospective cohort study EAR Parotidectomy Middle Aged IMPAIRMENT medicine.disease humanities Parotid Neoplasms Surgery Parotid gland Radiation therapy medicine.anatomical_structure Otorhinolaryngology Nasopharyngeal carcinoma RADIATION Female Radiotherapy Adjuvant Unilateral hearing loss Audiometry medicine.symptom business |
| Zdroj: | Head and Neck: Journal of the Sciences and Specialties of the Head and Neck, 28(10), 902-908. Wiley Head and Neck, 28(10), 902-908. Wiley Subscription Services, Inc., A Wiley Company Hoboken van der Putten, L, de Bree, R, Plukker, J T, Langendijk, J A, Smits, C, Burlage, F R & Leemans, C R 2006, ' Permanent unilateral hearing loss after radiotherapy for parotid gland tumors ', Head and Neck, vol. 28, no. 10, pp. 902-908 . |
| ISSN: | 1043-3074 |
| Popis: | Background. The purpose of this retrospective study was to determine the long-term effects of radiotherapy on hearing function in patients who underwent parotidectomy and postoperative radiotherapy for unilateral tumors of the parotid gland.Methods, An extensive set of tests was used to measure hearing loss. The mean dose on middle ear, cochlea, and Eustachian tube was estimated with a CT-planning system.Results. A hearing loss of >= 15 dB in 3 frequencies was found in 32% of the 52 patients included in the study. Patients with an asymmetrical hearing loss received a higher mean dose on the hearing structures (p Conclusions. Radiation-induced hearing loss is a common complication. A mean dose of > 50 Gy on the cochlea should be avoided. (c) 2006 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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