The findings of CT and MRI in patients with metanephric adenoma
| Autor: | Yan-Bang Lian, Chen-Fei Li, Chaoyan Wang, Jing Yan, Yuan Zheng, Xue-Ping Zhang, Jingliang Cheng |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adenoma
Adult Male Pathology medicine.medical_specialty Computer tomography Histology Adolescent medicine.medical_treatment Radiography Renal cortex Metanephric adenoma 030218 nuclear medicine & medical imaging Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Parenchyma medicine Humans Aged medicine.diagnostic_test business.industry Nutrient artery Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Kidney Neoplasms Nephrectomy medicine.anatomical_structure 030220 oncology & carcinogenesis Immunohistochemistry Female Radiology Tomography X-Ray Computed business Research Article |
| Zdroj: | Diagnostic Pathology |
| ISSN: | 1746-1596 |
| DOI: | 10.1186/s13000-016-0535-x |
| Popis: | Background Metanephric adenoma (MA) is a benign renal tumor that is difficult to distinguish from a malignant tumor via traditional radiography. The diagnosis of MA is often dependent on postsurgical histopathological examination. In the present report, the imaging features of MA on computer tomography (CT) and magnetic resonance imaging (MRI) were retrospectively evaluated. Methods Eight MA patients, 17–67 years of age, were pathologically confirmed and recruited between April 2009 and November 2014. Four of the eight patients were female. All patients underwent CT scanning, and one patient underwent MRI scanning. Three patients underwent CTA of the renal arteries. All patients underwent resection surgery (radical nephrectomy in five and nephron-sparing surgery in three patients). Results The average tumor size was 44.0 ± 23.6 mm. The lesions in 87.5 % cases were located both in the renal cortex and medulla and exhibited exophytic growth. Plain CT showed that MA tumors were solid, and the average CT value was 37.9 ± 6.7 HU. Dynamic contrast-enhanced CT revealed that enhanced degrees of MA tumors in the renal cortex, renal parenchymal, and pelvic phase were all lower than that of normal renal parenchyma. A slight enhancement in the renal cortex phase and an even higher enhancement in the renal parenchymal phase were observed in seven of the cases. Progressive enhancement in the pelvic phase was found in five cases and a slight decreased enhancement in the pelvic phase in two cases. MRI revealed that MA tumor was isointense on T1WI and isointense on T2WI with some slightly hyperintense areas in the center. CTA of the renal arteries revealed the nutrient artery in one patient and no nutrient artery in two. Immunohistochemical experiments demonstrated that most tumor cells were positive for vimentin, CK, and EMA. Conclusions MA is a rare benign renal neoplasm. Detailed knowledge of the CT and MRI characteristics of MA plays an important role in MA diagnosis and treatment. |
| Databáze: | OpenAIRE |
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