Production of interferon gamma and interleukin 17A in chicken T-cell subpopulations hallmarks the stimulation with live, irradiated and killed avian pathogenic Escherichia coli

Autor:	Sina Bagheri, Surya Paudel, Viskam Wijewardana, Richard Thiga Kangethe, Giovanni Cattoli, Michael Hess, Dieter Liebhart, Taniya Mitra
Rok vydání:	2022
Předmět:	T-Lymphocytes Immunology Interleukin-17 Receptors Antigen T-Cell gamma-delta Interferon-gamma Escherichia coli Leukocytes Mononuclear Animals Cytokines RNA Messenger Chickens Escherichia coli Infections Poultry Diseases Developmental Biology
Zdroj:	Developmental and comparative immunology. 133
ISSN:	1879-0089
Popis:	Avian pathogenic Escherichia coli (APEC) causes colibacillosis with different clinical manifestations. The disease is associated with compromised animal welfare and results in substantial economic losses in poultry production worldwide. So far, immunological mechanisms of protection against colibacillosis are not comprehensively resolved. Therefore, the present study aimed to use an ex vivo model applying chicken mononuclear cells stimulated by live and inactivated APEC. For this purpose, an 8-color flow cytometry panel was set up to target viable chicken immune cells including CD45
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8649ddbbc8c5f5a99cba883876ea2b52 https://pubmed.ncbi.nlm.nih.gov/35390358 Zobrazit plný text záznamu Full Text from ScienceDirect