HELLP Syndrome with and without Eclampsia
| Autor: | Marc Parrish, Laura Bufkin, Julie Cushman, Warren L. May, James N. Martin, Sharon D. Keiser, Michelle Y. Owens |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
HELLP Syndrome medicine.medical_specialty Adolescent HELLP syndrome Birth weight Blood Pressure Comorbidity Risk Assessment Young Adult Pregnancy Infant Mortality medicine Birth Weight Humans Eclampsia Retrospective Studies Obstetrics business.industry Incidence Infant Newborn Pregnancy Outcome Obstetrics and Gynecology Retrospective cohort study medicine.disease Hemolysis Parity Pediatrics Perinatology and Child Health Apgar Score Female Apgar score business |
| Zdroj: | American Journal of Perinatology. 28:187-194 |
| ISSN: | 1098-8785 0735-1631 |
| DOI: | 10.1055/s-0030-1266155 |
| Popis: | We assessed pregnancy outcomes for patients with HELLP syndrome (hemolysis; elevated liver enzymes; low platelet count) with and without concurrent eclampsia. We performed a retrospective investigation of data spanning three decades of patients with class 1 or 2 HELLP syndrome with concurrent eclampsia (HELLP + E) and patients with HELLP syndrome without eclampsia. Data were analyzed by appropriate tests for continuous or categorical outcomes with differences considered significant if P < 0.05. During 1981 to 1996 and 2000 to 2006, there were 693 patients with class 1 or 2 HELLP syndrome; altogether, 70 patients had HELLP + E. The only demographic difference was greater nulliparity in HELLP + E patients. Otherwise, inconsistent and clinically insignificant differences were observed between groups. Despite the relatively large size of the study groups, we were unable to detect a significant worsening of maternal or perinatal outcome in HELLP + E patients compared with HELLP patients. In our experience, eclampsia does not appear to contribute a significant adverse impact upon the course or outcome of HELLP syndrome pregnancies. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|