Neuromodulation via Focal Radiation: Radiomodulation Update
| Autor: | M. Bret Schneider, Brian P. Walcott, John R. Adler |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Basic science
medicine.medical_treatment Neurosurgery Brain tissue 030204 cardiovascular system & hematology Radiosurgery 03 medical and health sciences Neural activity 0302 clinical medicine radiomodulation Medicine behavioral disorders functional disorders Psychiatry business.industry General Engineering radiosurgery Neuromodulation (medicine) radiation psychiatric disorders Neurology neuromodulation Brain circuit business Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | When radiation is focally delivered to brain tissue at sub-ablative doses, neural activity may be altered. When done at a specific brain circuit node or connection, this is referred to as "radiomodulation." Radiation-induced effects on brain tissue, basic science, and clinical research that supports the radiomodulation hypothesis are reviewed in this article. We review progress in defining the necessary parameters in terms of dose, volumes, and anatomical location. It may be possible to deliver therapeutic neuromodulation that is non-invasive, non-destructive, and durable. |
| Databáze: | OpenAIRE |
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