Nanostructural control of transparent hydroxyapatite nanoparticle films using a citric acid coordination technique

Autor:	Zizhen Liu, Takuya Kataoka, Sadaki Samitsu, Daisuke Kawagoe, Motohiro Tagaya
Rok vydání:	2022
Předmět:	Mice Coordination Complexes Biomedical Engineering Animals Nanoparticles Calcium General Materials Science Hydroxyapatites General Chemistry General Medicine Porosity Citric Acid Cell Line
Zdroj:	Journal of Materials Chemistry B. 10:396-405
ISSN:	2050-7518 2050-750X
DOI:	10.1039/d1tb02002a
Popis:	Hydroxyapatite (HA), as the main mineral component in hard tissues, has good biocompatibility. In particular, HA films are widely used as bioactive coatings for artificial bones and dental implants in biomedical fields. However, it is currently difficult to prepare a nanostructure-controlled HA film by a wet process for further applications. Herein, we report the synthesis of HA nanoparticles coordinated by citric acid (Cit/HA) based on the interactions between carboxylate and calcium ions to control the sizes and shapes of the hybrid nanoparticles, to improve their dispersibility in water and to eventually form uniform transparent films with nanospaces, and investigated the film formation mechanism. As compared with the well-known rod-like HA nanoparticles (size: 48 × 15 nm
Databáze:	OpenAIRE
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