Basis for presentation of acid-base in two dimensions

Autor: James L. Gamble
Rok vydání: 1999
Předmět:
Zdroj: Advances in Physiology Education. 277:S136
ISSN: 1522-1229
1043-4046
Popis: Buffering of "metabolic" acid in tissues other than blood correlates closely with a change in extracellular bicarbonate concentration rather than with a change in extracellular pH. Of particular importance is the evidence for an absence of relation to change in pH. Questions are raised with respect to buffering mechanism, but simplification is offered for diagnosis. A clearer focus can be given to the guidepost changes in PCO2 and bicarbonate concentration. Basic relationships of buffering in the whole body are reviewed, and a modified diagnostic rationale is offered, based on a two-rather than a three-dimensional analysis.
Databáze: OpenAIRE