STUDY OF THE MICROCIRCULATION LEVEL IN BONE WITH OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES DURING THERAPY WITH RECOMBINANT ERYTHROPOIETIN, ROSUVASTATIN AND THEIR COMBINATIONS
| Autor: | A V Faitelson, O S Gudyrev, M V Pokrovskii, Rajkumar D.S.R. |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
medicine Osteoporosis Urology microcirculation osteoporotic fracture RM1-950 osteoporosis osteoporotic fracture microcirculation endothelial dysfunction recombinant erythropoietin rosuvastatin endothelial dysfunction recombinant erythropoietin Microcirculation Internal medicine microcirculat Pharmacology (medical) Osteoporotic fracture Rosuvastatin Endothelial dysfunction Recombinant erythropoietin Pharmacology business.industry medicine.disease osteoporosis Endocrinology Therapeutics. Pharmacology pharmacology business rosuvastatin medicine.drug |
| Zdroj: | Research Results in Pharmacology, Vol 1, Iss 1, Pp 47-50 (2015) Research Results in Pharmacology 1(1): 47-50 |
| Popis: | The experiment was carried out in female white Wistar rats. The effects of recombinant erythropoietin, rosuvastatin and their combination were investigated based on the blood supply to the bone after a modelled experimental osteoporosis. It was found that the studied drugs prevent decrease of bone microcirculation in cases of osteoporosis and in callus tissue in experimental osteoporotic fractures, positively influencing the course of reparative regeneration of bone tissue. |
| Databáze: | OpenAIRE |
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