| Autor: |
Zeyun Hao, Jinfu Tian, Hong Fang, Liang Fang, Xiao Xu, Feng He, Shaoya Li, Wenya Xie, Qiang Du, Xiaoman You, Debao Wang, Qiuhong Chen, Ruyi Wang, Shimin Zuo, Meng Yuan, Guo-Liang Wang, Lanqin Xia, Yuese Ning |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Cell Reports. 40:111235 |
| ISSN: |
2211-1247 |
| DOI: |
10.1016/j.celrep.2022.111235 |
| Popis: |
Rice blast and bacterial blight, caused by the fungus Magnaporthe oryzae and the bacterium Xanthomonas oryzae pv. oryzae (Xoo), respectively, are devastating diseases affecting rice. Here, we report that a rice valine-glutamine (VQ) motif-containing protein, OsVQ25, balances broad-spectrum disease resistance and plant growth by interacting with a U-Box E3 ligase, OsPUB73, and a transcription factor, OsWRKY53. We show that OsPUB73 positively regulates rice resistance against M. oryzae and Xoo by interacting with and promoting OsVQ25 degradation via the 26S proteasome pathway. Knockout mutants of OsVQ25 exhibit enhanced resistance to both pathogens without a growth penalty. Furthermore, OsVQ25 interacts with and suppresses the transcriptional activity of OsWRKY53, a positive regulator of plant immunity. OsWRKY53 downstream defense-related genes and brassinosteroid signaling genes are upregulated in osvq25 mutants. Our findings reveal a ubiquitin E3 ligase-VQ protein-transcription factor module that fine-tunes plant immunity and growth at the transcriptional and posttranslational levels. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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