Thrombocytopenia in children with malaria–A study from coastal Karnataka, India
Autor: | Guruprasada Shetty, K Shreedhara Avabratha, B Sanjeev Rai, Seema Gonsalves, Aby Dany |
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Rok vydání: | 2012 |
Předmět: |
Microbiology (medical)
medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Plasmodium falciparum Plasmodium vivax lcsh:Medicine Severity Internal medicine parasitic diseases medicine biology Acute febrile illness business.industry lcsh:R Significant difference Febrile illness Retrospective cohort study biology.organism_classification medicine.disease Thrombocytopenia Severe thrombocytopenia Malaria Infectious Diseases Falciparum infection business |
Zdroj: | Asian Pacific Journal of Tropical Disease, Vol 2, Iss 2, Pp 107-109 (2012) |
ISSN: | 2222-1808 |
Popis: | Objective: To study the occurrence and severity of thrombocytopenia in children with malaria. Methods: It was a retrospective study, done at Fr Muller Medical College Hospital Mangalore, in Karnataka, India. Data regarding all positive cases of malaria < 15 years admitted in the hospital between January 2010 to June 2011 were obtained. Patients were further assessed for thrombocytopenia and its severity. Data were analysed by Chi square test using SPSS version 13.0. Results: A total of 159 cases were included in the study with a mean age of presentation of 9 years. Plasmodium vivax was identified in 106 (66%) patients while Plasmodium falciparum in 26 (16%) and mixed infection in 27 (18%) patients. Thrombocytopenia was observed in 113 (71%) cases, of which 35 (31%) cases had mild, 49 (43%) cases moderate and 29 (26%) cases had severe thrombocytopenia. Thrombocytopenia was equally found in vivax and falciparum infection with no significant difference in severity between vivax and falciparum species. Conclusions: Thrombocytopenia is frequently seen in malaria and it is not dependent on type of malaria. In any acute febrile illness, thrombocytopenia should alert one to the possibility of malaria. |
Databáze: | OpenAIRE |
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