Comparison of the diagnostic performances of core needle biopsy in myxoid versus non-myxoid tumors
| Autor: | Cheol Lee, Hwan Seong Cho, Ilkyu Han, Himanshu Rohela, Yongsung Kim, Han-Soo Kim, Hye Jin Yoo |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Leiomyosarcoma Male Core needle medicine.medical_specialty Incisional biopsy Fibrosarcoma Chondrosarcoma Soft Tissue Neoplasms Fibroma Sarcoma Ewing Myxosarcoma Malignancy Sensitivity and Specificity 030218 nuclear medicine & medical imaging Sarcoma Synovial 03 medical and health sciences 0302 clinical medicine Histologic grade Biopsy medicine Humans Diagnostic Errors Aged medicine.diagnostic_test business.industry Myxoid tumor Soft tissue sarcoma Soft tissue Sarcoma General Medicine Middle Aged medicine.disease Liposarcoma Myxoid Tumor Burden Oncology Neurofibrosarcoma 030220 oncology & carcinogenesis Female Surgery Biopsy Large-Core Needle Radiology Neoplasm Grading business Myxoma Neoplasms Connective and Soft Tissue Neurilemmoma |
| Zdroj: | European Journal of Surgical Oncology. 45:1293-1298 |
| ISSN: | 0748-7983 |
| DOI: | 10.1016/j.ejso.2019.05.001 |
| Popis: | Background Despite the overall diagnostic utility of core needle biopsy (CNB) comparable to incisional biopsy, increased diagnostic errors have been suggested of CNB for myxoid soft tissue tumors. This study compared the diagnostic performance of CNB between myxoid and non-myxoid soft tissue tumors. Methods 369 patients who underwent ultrasound-guided CNB prior to resection for soft tissue tumors were classified into two groups according to resection pathology; myxoid group (n = 75) and non-myxoid group (n = 294). One-hundred and ninety-three patients were male and the median age of the patients was 40 years. Two-hundred and sixty-three tumors were malignant. Results CNB correctly diagnosed malignancy in 84% (58 of 69) for the myxoid group and 95% (184 of 194) for the non-myxoid group. For diagnosing histologic grade of soft tissue sarcoma, CNB correctly identified high grade in 78% (18 of 23) for the myxoid group and 74% (94 of 128) for the non-myxoid group. Correct diagnosis rate of histological type was significantly lower in the myxoid group (63% [47 of 75] in the myxoid group and 83% [242 of 294] in the non-myxoid group, p = 0.013). Conclusion Our study suggests that CNB is useful for myxoid soft tissue tumors of the extremity, with regard to diagnosing malignancy and histologic grade. However, CNB was less useful for identifying histologic subtype in myxoid tumors than in non-myxoid tumors. |
| Databáze: | OpenAIRE |
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