Thermoresponsive Nanogels Based on Different Polymeric Moieties for Biomedical Applications
| Autor: | Soheil Boddohi, Sobhan Ghaeini-Hesaroeiye, Ebrahim Vasheghani-Farahani, Hossein Razmi Razmi Bagtash, Esmaiel Jabbari |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Polymers and Plastics
Cancer therapy Bioengineering Nanotechnology Ether 02 engineering and technology Review 010402 general chemistry 01 natural sciences lcsh:Chemistry Biomaterials chemistry.chemical_compound Hydrophilic polymers nanogels lcsh:General. Including alchemy lcsh:Inorganic chemistry medicine lcsh:Science chemistry.chemical_classification Chemistry Organic Chemistry Polymer Vinyl ether 021001 nanoscience & nanotechnology Controlled release lcsh:QD146-197 0104 chemical sciences lcsh:QD1-999 Self-healing hydrogels Drug delivery drug delivery lcsh:Q thermoresponsive 0210 nano-technology lcsh:QD1-65 medicine.drug |
| Zdroj: | Gels Gels, Vol 6, Iss 20, p 20 (2020) |
| ISSN: | 2310-2861 |
| Popis: | Nanogels, or nanostructured hydrogels, are one of the most interesting materials in biomedical engineering. Nanogels are widely used in medical applications, such as in cancer therapy, targeted delivery of proteins, genes and DNAs, and scaffolds in tissue regeneration. One salient feature of nanogels is their tunable responsiveness to external stimuli. In this review, thermosensitive nanogels are discussed, with a focus on moieties in their chemical structure which are responsible for thermosensitivity. These thermosensitive moieties can be classified into four groups, namely, polymers bearing amide groups, ether groups, vinyl ether groups and hydrophilic polymers bearing hydrophobic groups. These novel thermoresponsive nanogels provide effective drug delivery systems and tissue regeneration constructs for treating patients in many clinical applications, such as targeted, sustained and controlled release. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|