Células C em tireóides de ratos pinealectomisados
| Autor: | Lilian Margareth Biagioni de Lima, Marcus Aurelho de Lima, Patrícia Fernanda Toledo Barbosa, Luiz Carlos Reis, Gilberto de Araújo Pereira, Leandro Luís Lopes Freitas, Maria de Fátima Borges |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: |
Male
Calcitonin medicine.medical_specialty Glândula Pineal pineal gland medicine.medical_treatment Thyroid Gland lcsh:Medicine Pinealectomy Cell Count Pineal Gland Statistics Nonparametric thyroid Rat Thyroid Pineal gland Internal medicine calcitonin Male rats medicine Animals rat Rats Wistar Calcitonina Células C Thyroid Analysis of Variance lcsh:R5-920 business.industry C Cells lcsh:R General Medicine Tiróide Rato Rats Endocrinology medicine.anatomical_structure c cells Rat lcsh:Medicine (General) business |
| Zdroj: | Revista do Hospital das Clínicas, Volume: 58, Issue: 1, Pages: 21-26, Published: 2003 Revista do Hospital das Clínicas v.58 n.1 2003 Revista do Hospital das Clínicas Universidade de São Paulo (USP) instacron:USP Revista do Hospital das Clínicas, Vol 58, Iss 1, Pp 21-26 Revista do Hospital das Clínicas, Vol 58, Iss 1, Pp 21-26 (2003) |
| Popis: | PURPOSE: To study quantitatively C cells in the thyroids of non-isogenic rats to determine the possible effects of pinealectomy on the number of these cells, and consequently on the synthesis and secretion of calcitonin. METHODS: Twenty male rats of an outbred strain (200-300 g) were used in the present study. One group of 10 animals was pinealectomized 50 days prior to sacrifice. Thyroid tissue was stained for calcitonin (Dako Corporation) at a 1:1500 dilution. The number of C cells observed was expressed as number of cells/cm². Data were analyzed statistically by Mann-Whitney test. RESULTS: The number of C cells in pinealectomized and normal animals ranged from 489 to 2084 per cm² and 227 to 1584 per cm², respectively, a difference that was statistically significant (P |
| Databáze: | OpenAIRE |
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